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Zepbound

$500-$1,100/mo

Can You Write Off Zepbound?

Short answer: Yes if prescribed to treat a diagnosed condition such as obesity or sleep apnea; it counts as a prescription medical expense.

Buying it without a prescription for general weight loss does not qualify. Medical costs are an itemized deduction only for the amount above 7.5% of your AGI, and only if your total itemized deductions beat the standard deduction ($16,100 single / $32,200 joint for 2026).

Records to keep: Keep receipts, statements (1098, 1098-T, 1099, W-2G), and a note of what each cost was for. Compare itemizing to the 2026 standard deduction before you claim.